The "Loss" meme originates from a 2008 *Ctrl+Alt+Del* webcomic strip by Tim Buckley, depicting a character's tragic experience with a miscarriage. The comic, known for its serious tone shift, became infamous online. "Loss" refers to the four-panel layout of the comic, which has been parodied extensively. Memes often reduce the strip to minimalist lines or shapes, representing the original comic's layout humorously or abstractly. This format highlights the absurdity of the original strip's abrupt tonal change and has been used to parody or comment on unrelated subjects, making "Loss" a versatile and enduring meme in internet culture.
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